Chengchen Guo

Assistant Professor, PhD

Email: guochengchen@westlake.edu.cn

Tel: +86 0571-86886859

Biography

Dr. Chengchen Guo received his B.S. degree from Nanjing University in 2011 and his Ph.D. in Chemistry from Arizona State University in 2017. He was a postdoctoral researcher in the Department of Biomedical Engineering at Tufts University from 2017 to 2020. He joined Westlake University in late 2020 as an Assistant Professor (Independent PI) in the School of Engineering, leader of the "Functional Biomaterials" laboratory, and deputy director of the Biomedical Engineering Program at Westlake University.

Research

The primary research focus is to develop functional biomaterials towards clinical translation with rational design and advanced processing. Some major research topics include:

1. Protein-based bioresorbable materials for bone tissue repair and regeneration;

2. Structure and properties of natural biopolymers (e.g. silk and collagen);

3. Functional biopolymer-based nanocomposites and their biomedical applications.

Representative Publications

1. Ziyang Sun, Ruochuan Huang, Hao Lyu, Xin Yu, Wenzhao Wang, Jinghang Li, Xingyu Lu, Chengchen Guo*, Silk Acid as an Implantable Biomaterial for Tissue Regeneration. Adv. Health. Mater. 2023, 2301439

2. Xin Yu†, Yang Hu†, Haoyuan Shi†, Ziyang Sun, Jinghang Li, Haoran Liu, Hao Lyu, Jiujie Xia, Jingda Meng, Xingyu Lu, Jingjie Yeo*, Qiyang Lu*, Chengchen Guo*, Molecular Design and Preparation of Protein-based Soft Ionic Conductors with Tunable Properties. ACS Appl. Mater. Interfaces 2022, 14, 42, 48061-48071

3. Hao Lyu, Jinghang Li, Zhechen Yuan, Haoran Liu, Ziyang Sun, Rui Jiang, Xin Yu, Yi Hu, Ying Pei, Jie Ding, Yi Shen*, Chengchen Guo*, Supertough and Highly Stretchable Silk Protein-based Films with Controlled Biodegradability. Acta Biomaterialia 2022, 153, 149–158

4. Niping Deng, Jinghang Li, Hao Lyu, Ruochuan Huang, Haoran Liu, Chengchen Guo*, Degradable Silk-based Soft Actuator with Magnetic Responsiveness. J. Mater. Chem. B 2022, 10, 7650-7660

 - “Journal of Materials Chemistry B 2022 Emerging Investigators Themed Issue”

5. Haoran Liu, Ziyang Sun*, Chengchen Guo*, Chemical Modification of Silk Proteins: Current Status and Future Prospects. Adv. Fiber Mater. 2022, 4, 705-719

6. Jinghang Li, Xin Yu, Eduardo Enciso Martinez, Jiaqing Zhu, Ting Wang, Shengwei Shi, Su Ryon Shin, Shabir Hassan*, Chengchen Guo*, Emerging Biopolymer-based Bioadhesives. Macromol. Biosci. 2021, 2100340

- Selected papers in “Best of Macromolecular Journals 2023 Edition”

7. Chengchen Guo†, Chunmei Li†, Hiep V. Vu, Philip Hanna, Aron Lechtig, Yimin Qiu, Xuan Mu, Shengjie Ling, Ara Nazarian, Samuel Lin, David L. Kaplan, Thermoplastic Moulding of Regenerated Silk. Nat. Mater. 2020, 19, 102-108. († equal contribution)

8. Chunmei Li†, Chengchen Guo†, Vincent Fitzpatrick, Ahmed Ibrahim, Myrthe Zwierstra, Philip Hanna, Aron Lechtig, Ara Nazarian, Samuel Lin, and David Kaplan, Design of biodegradable implantable devices towards clinical translation. Nat. Rev. Mater. 2020, 5, 61-81. († equal contribution)

9. Ying Chen†, Chengchen Guo†, Eleana Manousiouthakis, Xiuli Wang, Dana M. Cairns, Terrence Roh, Chuang Du, David L. Kaplan, Bi-layered Tubular Microfiber Scaffolds as Functional Templates for Engineering Human Intestinal Smooth Muscle Tissue. Adv. Funct. Mater. 2020, 2000543. († equal contribution)

10. Chengchen Guo, Chunmei Li, Xuan Mu, David L. Kaplan, Engineering Silk Materials: From Natural Spinning to Artificial Processing. Appl. Phys. Rev. 2020, 7, 011313